Format: ORAL

E.G.Wesely1 and L.Thamaraiselvi 2

1. Department of Botany, Arignar Anna Government Arts College, Namakkal – 637 002, India 2. Department of Botany, Arignar Anna Government Arts College, Namakkal – 637 002, India

Medicinal plants have been identified and used in traditional medicine all over the world since the dawn of civilization. Medicinal plants are a rich source of novel drugs, which are used in traditional medical systems (Bauri et al., 2015). More than 50,000 plant species are reported to be used for medicinal purposes around the world.Diabetes mellitus (DM) is a metabolic disorder caused by an insufficient amount of insulin in the body, either during its production or action, or both (Mukhtar et al., 2019). If DM is not treated properly, serious complications such as muscular tissue damage, retinopathy, neuropathy, nephropathy, heart complications, and ulceration problems can occur. Insulin and glucagon are pancreatic hormones that regulate blood glucose levels in a normal range based on the bodys needs (Arden and Ramsey, 2015).Although synthetic drugs are primarily used to treat diabetes, they have significant and irreversible side effects, and their accessibility to the general public is also difficult due to their high cost (Amin et al., 2013). Little research has been done on the anti-diabetic properties of ethanolic extract of leaves and stems Plumbago zeylanica, Neolitsea cassia and Wrightia tinctoria. Due to the rising prevalence of diabetes, antihyperglycemic drugs are in high demand. Because of the minimal side effects and medicinal importance of ethanolic extract of Plumbago zeylanica, Neolitsea cassia and Wrightia tinctoria, the current study is being conducted to conduct antidiabetic studies.The results of the study suggest that the ethanol extract of the leaves and stems has antidiabetic properties. Oral hypoglycaemics such as acarbose, which belongs to the -amylase inhibitor class, have been shown to inhibit alpha-amylase. As a result, in the assays, acarbose was used as a positive control.